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Rimadyl for Dogs

Rimadyl is the original brand name for carprofen, a prescription non-steroidal anti-inflammatory drug (NSAID) for dogs. Vets prescribe it mainly to relieve the pain and inflammation of osteoarthritis and to control pain after surgery. It is made by Zoetis, sold as flavored chewable tablets and caplets in 25 mg, 75 mg and 100 mg strengths, and it requires a veterinary prescription in the United States. Generic carprofen — Novox, Vetprofen, Carprovet, Carprieve and others — is the same active drug at the same strengths, usually for less money.

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Quick facts Rimadyl at a glance
Rimadyl (carprofen) key facts
Generic nameCarprofen
Drug classNSAID, propionic acid class (related to ibuprofen, naproxen and ketoprofen)
ManufacturerZoetis (originally developed by Pfizer Animal Health)
Approved forDogs only — not cats, and not people
Main usesOsteoarthritis pain and inflammation; post-operative pain (soft tissue and orthopedic surgery)
FormsFlavored chewable tablet, caplet, and an injectable solution given in-clinic
Tablet strengths25 mg, 75 mg, 100 mg
Label dose2 mg per lb of body weight per day — once daily, or split into 1 mg per lb twice daily
Prescription statusPrescription-only (Rx). Never sold over the counter in the U.S.
Onset of reliefCommonly reported within 1–3 hours of a dose

What Is Rimadyl?

Rimadyl is a brand of carprofen, which is the actual drug. That single fact answers most of the confusion around the name: "Rimadyl," "the drug Rimadyl," "canine Rimadyl" and plain "carprofen" all refer to the same molecule. Rimadyl was the first carprofen product approved for dogs in the United States and it dominated the market for years, which is why so many owners hear the brand name at a checkup and only later learn the generic name.

Rimadyl belongs to the propionic acid class of NSAIDs — the same broad family as ibuprofen, naproxen and ketoprofen in human medicine. That family resemblance is exactly why it is dangerous to reason from human medicine here: dogs metabolize these drugs very differently, and the human versions are not safe substitutes for carprofen. Rimadyl is formulated, dosed and approved specifically for dogs.

Compared with steroids, carprofen is usually the better fit for long-term use: it reduces inflammation, pain and fever with fewer of the whole-body side effects steroids cause. It is also considered safer for dogs than human NSAIDs such as ibuprofen, naproxen or aspirin, which can poison dogs even at small doses.

Today Rimadyl competes with several FDA-approved generics that contain the identical active ingredient. See our Rimadyl vs generic carprofen comparison for what actually differs between them, and our complete carprofen for dogs guide for the underlying pharmacology.

What Is Rimadyl Used For in Dogs?

Rimadyl is approved for two core jobs, and most prescriptions fall into one of them:

  • Osteoarthritis pain and inflammation. This is the long-term use. Arthritic dogs take Rimadyl for months or years to stay comfortable and mobile. If you are still working out whether your dog's stiffness is arthritis, see our guide to signs a dog needs arthritis pain relief.
  • Post-operative pain. This is the short-course use — typically a few days to a couple of weeks after a spay, neuter, dental procedure, or orthopedic surgery such as a cruciate repair. Many clinics give the injectable form before the dog wakes up, then send tablets home.

Vets also prescribe it for soft-tissue injuries, sprains and other acute musculoskeletal pain, and sometimes for fever. What Rimadyl does not do is treat infection — it is not an antibiotic — and it does not repair a damaged joint. It reduces the pain and swelling that come from the damage.

How Rimadyl Works

Injured or arthritic tissue produces prostaglandins, signalling chemicals that drive pain, swelling and heat. Carprofen blocks the cyclooxygenase (COX) enzymes that manufacture them, so the inflammatory signal quiets down and the dog feels better. Most owners see a difference the same day; the label and common clinical experience put meaningful relief somewhere in the first one to three hours after a dose.

The same mechanism explains the drug's risks. Prostaglandins also help protect the stomach lining and help regulate blood flow through the kidneys, so blocking them is never entirely free of consequence. That trade-off is the reason for the monitoring described below.

Rimadyl Strengths, Chewables and Caplets

Rimadyl tablet strengths and typical dog size
StrengthFormTypically used forStrength guide
25 mgChewable / capletSmall dogs, or fine-tuning a larger dog's totalCarprofen 25mg
75 mgChewable / capletMedium dogsCarprofen 75mg
100 mgChewable / capletMedium-to-large dogsCarprofen 100mg

Chewable vs caplet. Rimadyl chewable tablets are flavored and most dogs take them like a treat, which is the main reason vets reach for them. Caplets are unflavored and usually need to go in food or down the throat. Both are the same drug at the same strength, and both are scored so a vet can prescribe a half tablet. The flavoring is also a hazard worth respecting: a palatable tablet is one a dog will happily eat a whole bottle of, which is a common route to carprofen overdose. Store it accordingly.

If you are trying to identify a tablet you already have, our carprofen tablet and pill identifier guide covers the imprints and appearance of the common brands.

Rimadyl Dosage for Dogs

The labeled dose is 2 mg per pound of body weight per day, given either as one daily dose or split into 1 mg per pound twice daily, roughly 12 hours apart. Because dosing is weight-based, an accurate current weight matters — a dog who has gained or lost several pounds may need a different tablet.

Not a prescription Reference only

Only your veterinarian can set your dog's Rimadyl dose. They account for weight, bloodwork, age, other medications and the condition being treated. Never start, change or stop a dose on your own.

For the full weight-band breakdown, including kilograms and how strengths get combined, see our Rimadyl dosage guide or the interactive carprofen dosage calculator. The math is identical for Rimadyl and every generic carprofen, because the active ingredient is the same. If a dose gets missed, read what to do about a missed carprofen dose rather than doubling up.

Rimadyl Side Effects in Dogs

Most dogs tolerate Rimadyl well, and many take it for years without trouble. The side effects that do occur mostly involve the digestive tract, the liver and the kidneys.

Common and usually mild: reduced appetite, vomiting, soft stool or diarrhea, and lethargy. Giving the tablet with food helps some dogs. A dog who seems unusually quiet, sleepy or "off" in the first days is a frequent owner report — see does carprofen make dogs sleepy? and carprofen, diarrhea, vomiting and panting.

Call your vet promptly if you see: repeated vomiting, black or tarry stool, blood in vomit or stool, yellowing of the gums, eyes or skin (jaundice), a marked increase in drinking or urinating, stumbling or seizures, or any sudden behavior change. These can signal a gastrointestinal ulcer, liver injury or kidney problem, and they are reasons to stop the drug and be seen, not to wait and watch.

Higher-risk dogs include those with existing kidney or liver disease, dehydration, bleeding disorders, or a previous reaction to any NSAID, and dogs already taking a corticosteroid such as prednisone or another NSAID. Combining NSAIDs, or an NSAID with a steroid, sharply raises ulcer risk. Our drug interactions guide and kidney and liver disease guide go into detail, and carprofen and gabapentin covers one pairing vets do commonly use together.

The full symptom-by-symptom guide, including how Rimadyl side effects are treated and how long they last after stopping, is on our Rimadyl and carprofen side effects page.

Bloodwork and Long-Term Monitoring

Because carprofen is processed by the liver and affects kidney blood flow, vets typically run baseline bloodwork before starting a dog on long-term Rimadyl, recheck after the first few weeks, and then continue about every three to six months. The point is to catch a change early, while it is still reversible and before the dog looks sick.

This is also why "my friend's dog has leftover Rimadyl" is a genuinely bad idea: the monitoring, not just the tablet, is what makes long-term NSAID use reasonably safe. See bloodwork monitoring on carprofen and how long a dog can stay on carprofen.

Who Should Not Take Rimadyl

  • Cats. Rimadyl is not approved for cats, which clear carprofen far more slowly and are much more vulnerable to kidney injury. See carprofen for cats.
  • People. Carprofen was studied in humans decades ago and withdrawn. See carprofen for humans.
  • Dogs with a known carprofen or NSAID hypersensitivity, or active GI ulceration.
  • Very young puppies, and pregnant or nursing dogs — safety has not been established in these groups. See Rimadyl and carprofen for puppies.
  • Dogs on another NSAID or a corticosteroid, unless a vet has deliberately planned a transition with a washout period.

Is Rimadyl Available Over the Counter?

No. Rimadyl is prescription-only in the United States, in every strength and every form, and no legitimate pharmacy will dispense it without a valid prescription from a veterinarian who has examined your dog. Listings promising "Rimadyl without a vet prescription" are a warning sign about the seller, not a shortcut — carprofen needs weight-based dosing and bloodwork monitoring, which is precisely why the prescription requirement exists. Our page on why carprofen requires a prescription explains the rules and how to get a prescription filled quickly and legally.

Rimadyl Cost and Generic Alternatives

As the brand-name product, Rimadyl is usually the most expensive way to buy carprofen. The generics are FDA-approved, bioequivalent, and frequently a fraction of the price — which matters a great deal when a large dog may take the drug daily for years.

Rimadyl and its FDA-approved generic equivalents
ProductTypeGuide
Rimadyl (Zoetis)BrandThis page
NovoxGeneric carprofenNovox for dogs
VetprofenGeneric carprofenVetprofen for dogs
CarprovetGeneric carprofenCarprovet for dogs
Other brandsGeneric carprofenAll generic carprofen brands compared

Ask your vet for a written prescription so you can price-shop, then compare pharmacies on our where to buy carprofen page. Our cost and insurance guide covers whether pet insurance is likely to help. If cost is the reason you are considering stopping treatment, raise it with your vet directly — a generic switch is usually an easy conversation.

Pros and Cons of Rimadyl for Dogs

Weighing Rimadyl for your dog
ProsCons
Strong, well-studied pain and inflammation reliefCan irritate the stomach and cause ulcers
Works within hours; suits short and long coursesRare but serious liver or kidney reactions
FDA-approved for dogs, with cheaper genericsNeeds a prescription and periodic bloodwork
Flavored chewable is easy to giveCannot be combined with steroids or other NSAIDs

Arthritis pain that goes untreated also costs a dog its quality of life, so the question is usually how the small risk of side effects compares with the large benefit for an otherwise healthy dog. Tell your vet about every other medicine and condition so they can make that call.

Alternatives to Rimadyl

If Rimadyl is not tolerated or not enough on its own, vets have other options: other canine NSAIDs such as meloxicam, firocoxib (Previcox) and deracoxib (Deramaxx), the non-NSAID Galliprant, monoclonal antibody injections, joint injections, and non-drug measures like weight management, physical therapy and joint supplements. Many vets build a multimodal plan, with Rimadyl as one part alongside joint supplements, massage, acupuncture, chiropractic care or hydrotherapy. Start with our NSAIDs for dogs overview, meloxicam vs carprofen, and carprofen alternatives.

Prescription required Rimadyl is prescription-only

Rimadyl requires a valid veterinary prescription, and the right dose depends on your dog's weight and health history. This page is educational and is not a substitute for your vet's instructions.

Frequently Asked Questions

What is Rimadyl used for in dogs?

Rimadyl is used to relieve the pain and inflammation of osteoarthritis and to control pain after soft tissue or orthopedic surgery. Vets also prescribe it for sprains, soft-tissue injuries and other acute musculoskeletal pain.

What is the generic name for Rimadyl?

Carprofen. FDA-approved generic carprofen brands include Novox, Vetprofen, Carprovet, Carprieve, Rovera, OstiFen, Quellin and Truprofen — all the same active ingredient at the same strengths.

Is Rimadyl the same as carprofen?

Yes. Rimadyl is a brand name for the drug carprofen. A dog prescribed Rimadyl and a dog prescribed generic carprofen at the same strength are getting the same medication.

Is Rimadyl an NSAID and an anti-inflammatory?

Yes to both. NSAID stands for non-steroidal anti-inflammatory drug, so Rimadyl (carprofen) is an anti-inflammatory that relieves pain by reducing inflammation, without being a steroid. It belongs to the propionic acid class, the same broad family as ibuprofen, naproxen and ketoprofen — but formulated and approved specifically for dogs.

How long does Rimadyl take to work?

Pain relief is commonly reported within one to three hours of a dose. For arthritis, the fuller benefit is usually clearer after several days of consistent dosing.

Does Rimadyl make dogs sleepy?

Lethargy is a recognized side effect, and some owners notice their dog is quieter in the first few days. Marked or worsening lethargy is not something to wait out — contact your vet, because it can also signal a liver or kidney problem.

Is Rimadyl safe for dogs long term?

Many dogs take Rimadyl safely for years under veterinary supervision with periodic bloodwork to monitor liver and kidney function. Dogs with existing kidney, liver or GI disease are at higher risk and need closer assessment.

How much does Rimadyl cost?

It varies by strength, quantity and pharmacy, but brand-name Rimadyl is typically the most expensive carprofen option. FDA-approved generics contain the same drug and usually cost considerably less.

Is Rimadyl available over the counter?

No. Rimadyl is prescription-only in the U.S. in all strengths and forms. Any seller offering it without a prescription should be treated as illegitimate.

Can I give my dog Rimadyl and ibuprofen?

No. Never give a dog ibuprofen, and never combine two NSAIDs or an NSAID with a steroid unless your vet has specifically directed it — the combination sharply increases the risk of stomach ulcers and kidney injury.

Can cats take Rimadyl?

Rimadyl is not approved for cats. Cats clear carprofen much more slowly than dogs and are far more susceptible to kidney injury, so feline use is rare and strictly a veterinary decision.

Is there an injectable form of Rimadyl?

Yes. An injectable carprofen solution is given in the clinic, often before surgery, with tablets continuing at home afterwards.

Is Rimadyl better than steroids for dogs?

For long-term arthritis care vets usually prefer an NSAID like Rimadyl because it has fewer side effects than steroids. The two must not be given together.

What are the pros and cons of Rimadyl?

Rimadyl is effective, fast-acting and FDA-approved for dogs, but it can cause stomach upset or ulcers, rarely harms the liver or kidneys, and needs a prescription and periodic bloodwork.

How do I report a Rimadyl side effect?

Stop the medicine and call your vet first. You can also report a suspected reaction to Zoetis at 1-888-963-8471.

What is Rimadyl for dogs 100mg?

Rimadyl for dogs 100mg is the largest strength of the Zoetis brand carprofen, sold as a chewable tablet and as a caplet. The Rimadyl for dogs 100mg chewable is typically used for larger dogs, as directed by your vet.

What is the difference between Rimadyl 25 mg, 75 mg and 100 mg?

Rimadyl 25 mg for dogs, Rimadyl 75 mg for dogs and Rimadyl 100 mg chewables are strengths of the same drug. Dogs of different weights need different tablet combinations.

Is there a generic for Rimadyl for dogs?

Yes. Generic for Rimadyl for dogs means generic carprofen, such as Novox, Vetprofen, Carprovet, Carprieve and Rovera. A generic Rimadyl 100mg for dogs has the same active ingredient. See generic alternatives.

Do I need a Rimadyl prescription for dogs?

Yes. A Rimadyl prescription for dogs comes from your vet. You can then purchase Rimadyl for dogs from your vet clinic or a licensed pet pharmacy, including Pet Meds, see where to buy carprofen.

What is dog medicine Rimadyl used for?

Dog medicine Rimadyl is used to relieve the pain and inflammation of arthritis and to control pain after surgery.

What the FDA and Major Veterinary References Say

This is a plain-language summary of public statements from regulators and veterinary references. We link each source so you can read the original, and your own vet’s advice always comes first.

  • FDA: Get the Facts about Pain Relievers for Pets
    Lists carprofen among the FDA-approved NSAIDs for dogs, approved to control pain and inflammation from osteoarthritis and after soft-tissue or orthopedic surgery. FDA also advises calling your veterinarian before giving any medication, because a drug meant for you or another pet may not be right for your dog.
  • FDA-approved Rimadyl labeling (Animal Drugs @ FDA)
    The label says dogs should have a history and physical exam before NSAID therapy, and that baseline blood tests, repeated periodically, should be considered. It is not recommended for dogs with bleeding disorders, and safety is not established for puppies under 6 weeks, pregnant, breeding or nursing dogs. As an NSAID class, carprofen can affect the stomach and intestines, kidneys and liver.
  • Merck Veterinary Manual: NSAIDs in Animals
    Describes NSAIDs as routinely used to relieve pain and inflammation from osteoarthritis in dogs, and notes they provide symptomatic relief and do not significantly change the underlying joint damage.

Sources & Further Reading

  • FDA Center for Veterinary Medicine — Freedom of Information Summaries for carprofen products (NADA/ANADA approvals)
  • Zoetis Rimadyl (carprofen) prescribing information and client information sheet
  • DailyMed (U.S. National Library of Medicine) — carprofen product labels, including chewable tablet, caplet and injection formulations
  • FDA — Get the Facts about Pain Relievers for Pets (NSAID owner guidance)
  • Plumb's Veterinary Drug Handbook — carprofen monograph
  • American Veterinary Medical Association (AVMA) — NSAID use in companion animals

This page summarizes and explains publicly available veterinary drug information. It is not a substitute for the official prescribing information your vet or pharmacist provides with your specific prescription.

Editorial note
Written by the Carprofen.com editorial team. See our editorial policy. Last updated 2026-10-26. This information is educational and does not replace advice from your veterinarian.